Here are quick-hit previews of the top four games on the Week 5 schedule in the NFL.

1. Patriots (3-1) at Broncos (4-0), 4:15PM ET
Several pundits have remarked that the Patriots are back after beating the Falcons and Ravens in back to back weeks. But some of their struggles still remain. For the most part, Baltimore marched up and down the field on New England’s defense in Week 4 and if it weren’t for a couple of key drops in the red zone, the Ravens could have walked out of Foxboro with a victory. The Broncos need to pressure Tom Brady for four quarters and not stop what has worked for them the first four weeks. Offensively, Knowshon Moreno will have the opportunity to shine today in his first start and as long as Kyle Orton doesn’t turn the ball over, Denver could pull off the small upset.

2. Bengals (3-1) at Ravens (3-1), 1:00PM ET
Who would have thought this would be a big game in Week 5? The Ravens are still seething from their loss to the Patriots last weekend and will look to take it out on an underrated Bengals team. Cincinnati’s 3-1 record is no fluke – they beat the Packers in Green Bay and the defending champion Steelers at home. While they didn’t play well last week in an overtime with over Cleveland, the Bengals proved that they could still wind up victorious even when they make mistakes. Carson Palmer and company won’t get away with turning the ball over today, however. The Ravens feast off turnovers and Cincinnati’s defense will be challenge to slow down Joe Flacco, Ray Rice and the potent Baltimore offense. This game will be a great test to see where the Bengals are.

3. Falcons (2-1) at 49ers (3-1), 4:05PM ET
Nobody wants to define either of these teams. Before the Falcons lost to the Patriots in Week 3, many people thought they were an elite squad. Plenty of pundits want to crown the 49ers a legitimate playoff team, but they need to sustain momentum and beat a good Atlanta team at home. Even without Frank Gore, this is a game San Francisco can control. The Falcons have had issues stopping the run and if the Niners can get Glen Coffee going early, it could open things up for Shaun Hill and the passing game. Mike Singletary’s defense has been great up to this point and if they sell out to stop Michael Turner and the Falcons’ running game, they better be prepared to double team tight end Tony Gonzalez and slow Matt Ryan in the passing game. This should be a fun matchup throughout.

4. Texans (2-2) at Cardinals (1-2), 4:15PM ET
It’s time for one of these teams to step up. The Texans have more than enough offensive weapons to make a playoff run but their defense has issues stopping the run and keeping opponents out of the end zone. The Cardinals have dinked and dunked their way through the first three games but Kurt Warner needs to start testing defenses vertically or else this team will continue to struggle. This is actually a good matchup for Houston because Arizona doesn’t pose much of a ground threat and the Texans have a decent pass defense. If the Cards can’t get Beanie Wells and Tim Hightower going, they will have trouble building and sustaining a lead today. And if they can’t take control of this game, they’ll be at risk of once again losing at home, where they were so dominant last year.

According to Adam Schefter’s Twitter page, Colts defensive end Dwight Freeney is expected to miss 2-3 weeks due to a right quad injury and 49ers.com reports that Frank Gore will miss three weeks with a high right ankle and a right hind foot sprain.

I don’t know if “devastating” is the right word to describe these injuries, but they’re both significant.

The Colts defense has played excellent so far this year, partly because they’ve been able to generate pressure using only their front four. Freeney has been a one-man wrecking crew at times, especially last Sunday night in Arizona. With him out, Indy might not be able to create pressure solely from their front four and it could change the way they game plan.

If rookie Glen Coffee can pick up where he left off in preseason, then the Niners will stay afloat without Gore for a couple weeks. Coffee showed a surprising burst and quickness in preseason and will now have to become a full-time back in just his first year.

What will be interesting to watch unfold is if Coffee can’t be productive. That would put pressure on Shaun Hill to make more plays in the passing game and outside of his play at Minnesota on Sunday and the game-winning drive in Arizona in Week 1 he hasn’t done that.

If San Fran wants to stay atop the NFC West, it’s time for Hill to step up and give the Niners a balanced offensive attack while Gore is out.

Along with the odds and over/under totals, here’s a look at some of the marquee matchups for Week 3 in the NFL.

Falcons (2-0) at Patriots (1-1), Sunday, 1:00PM ET
This will be a great test to see where both of these teams currently lie. The Falcons are 2-0 with wins over two struggling 2008 playoff teams, while the Patriots could very easily be 0-2 right now. Behind quarterback Matt Ryan’s (108.5 QB Rating) great start, Atlanta’s offense is gearing up for big things this season, but the defense is giving up 5.1 YPC and just lost starting DT Peria Jerry for the year. New England has its own defensive problems without middle linebacker Jerod Mayo and Tom Brady still hasn’t looked comfortable on his surgically repaired knee. It would be unwise to doubt Bill Belichick and the Patriots, but the Falcons would go a long way in proving that they’re a legitimate Super Bowl contender with a win at Foxboro.
Odds: Patriots –4.

49ers (2-0) at Vikings (2-0), Sunday, 1:00PMET
Who would have thought that the only matchup this week featuring two 2-0 teams would be the 49ers at Vikings? San Francisco’s defense has been solid in the first two games, yielding less than 300 total yards per game and limiting opponents to only 13 PPG. But neither Arizona nor Seattle posed the rushing threat that Adrian Peterson and Minnesota will provide this Sunday. This will be a great test to see where Mike Singletary’s team is and whether or not the Niners are legitimate playoff contenders. Can Shaun Hill beat the Vikings through the air if/when the Williams Wall takes away Frank Gore?
Odds: Vikings –7.

Titans (0-2) at Jets (2-0), Sunday, 1:00PM ET
Panic hasn’t set in yet for Jeff Fisher and the Titans, although a loss this week in East Rutherford would make things unsettling in Tennessee. Jets’ rookie Mark Sanchez has looked more like a five-year pro than a quarterback with only two career starts under his belt, but will this be the week that he finally suffers some growing pains? Tennessee’s defense has a way of making opposing quarterbacks look bad, although that certainly wasn’t the case last week when Houston’s Matt Schaub threw a career high four touchdown passes against the Titans. If Fisher’s squad falls to 0-3, the Titans may never recover. On the flip side, if the Jets start 3-0 they’ll set themselves up for making a run at the AFC East crown.
Odds: Jets –2.5.

(2-0) Colts at Cardinals (1-1), Sunday, 8:20PM ET
If you like watching quick-tempo offenses, then the Sunday night game will be right up your alley. The Colts defeated the Dolphins on Monday might despite only running 35 plays, which means Peyton Manning and the rest of Indy’s offense is already in midseason form. The Cards bounced back from their opening week loss to the 49ers by pounding the Jaguars last Sunday thanks to Kurt Warner’s amazing 24-for-26 passing day. Watching Manning and Warner dissect the opposing defense is going to be one of the more intriguing things to watch in Week 3.
Odds: Cardinals -2.5.

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NFL preseason action continues tonight with four games on the schedule. Below are six quick-hit thoughts and things to watch for during tonight’s slate of games.

1. Are the reports true about Palmer?
All indications from Bengals camp is that Carson Palmer is in the best shape of his career after missing virtually the entire 2008 season with a right elbow injury. Palmer is expected to get 12-15 snaps tonight when the Bengals travel to New Orleans to take on the Saints. Just as the Patriots were hoping for a strong showing from Tom Brady last night (he threw for 100 yards and 2 TDs, by the way), Cincinnati is hoping that Palmer flashes the arm strength that once made him the top overall pick. Another thing to keep an eye on is how the young Cincinnati offensive line looks in protecting Palmer. The Bengals have a physical unit in Andrew Whitworth, Anthony Collins, Kyle Cook, Nate Livings and Bobbie Williams, but they’re an inexperienced unit on a whole and Cincy would love to see some cohesion from the group tonight.

2. The starting quarterback battle for the Vikings begins tonight.
Head coach Brad Childress reported that Sage Rosenfels will get the start Friday night against the Colts, which isn’t a huge surprise considering Tarvaris Jackson missed some time in camp with a sprained knee. Still, Rosenfels getting the starting nod tonight may be an indication that he’s pulled ahead in the race for the Vikes’ starting quarterback job. Rosenfels doesn’t have a high ceiling in terms of potential, but he’s steady and could be a good game manager for a Minnesota team that is expected to keep the ball on the ground a lot with Adrian Peterson. While Jackson will certainly get his opportunity to start in preseason, a strong first impression tonight would go a long way for Rosenfels.

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Sunday’s Best: Giants (11-2) at Cowboys (8-5), 8:15 PM ET NBC
We’re getting down to crunch time in the NFL and there’s nothing better than an NFC East battle with playoff implications. If the regular season ended today, the Cowboys would be in as the sixth seed. But the regular season doesn’t end today and Dallas has one of the toughest final stretches of any team with playoff aspirations. After playing host to the Giants on Sunday night, they’re home against the Ravens next week and then travel to Philadelphia in the season finale. That’s a brutal three-game stretch for any team, nevertheless one that is dealing with injuries (see Marion Barber) and internal bickering (see Cowboys’ wideouts vs. Tony Romo). The Giants, meanwhile, are sitting pretty for the top seed in the NFC, but they’ll have to earn it after losing to the Eagles at home last Sunday. Suddenly the Carolina Panthers are just one game behind the Giants in the quest for capturing home field advantage throughout the postseason and the two teams play each other next week in Jersey. Can the Cowboys bounce back from their collapse last Sunday in Pittsburgh? Will the Giants lose two in a row for the first time all season? Like several matchups on the Week 15 schedule, this game is must-see.

Upset Watch: 49ers (5-8) at Dolphins (8-5), 1:00 PM ET, FOX
Let me state for the record that I think the Dolphins have been one of the best storylines in the NFL this season. That said – they’re due for a letdown. Just when the public is ready to hop on a team’s bandwagon and ride its coattails the rest of the season, they hit a pothole and send everyone flying off. Miami is a better team than San Francisco and they should win Sunday in convincing fashion. But San Fran is a dangerous team right now because they have nothing to play for and have fiery Mike Singletary leading the way – the same fiery Mike Singletary that is trying to prove he deserves a head-coaching job. The Niners have been more competitive since Singletary took over and quarterback Shaun Hill has been a pleasant surprise. You might think I’m crazy (and I am) for predicting a 49er upset considering Frank Gore is expected to miss the game, but DeShaun Foster is no slouch and is likely craving the opportunity to carry the full load. Just when you think you’ve got the NFL figured out, it throws you a punch to the gut. Do we have another punch coming this Sunday in Miami?

Intriguing Matchup: Buccaneers (9-4) at Falcons (8-5), 1:00 PM ET, FOX
Call this “Sunday’s Best II.” With the Bucs’ loss to the Panthers in Carolina on Monday night, the NFC South is now 0-10 this season when playing on the road against other NFC South opponents. And considering Jeff Garcia has missed significant practice time this week due to a calf injury, things don’t bode well for Tampa. However, Monte Kiffin’s defense has always given the Falcons trouble. Both of these teams are coming off of divisional losses and both need a win to stay in the NFC playoff picture (especially Atlanta), so we can probably expect one hell of a fight. Look for Tampa to take away Michael Turner and the Falcons’ running game and force rookie Matt Ryan to beat them through the air. They had this same approach in their Week 2 victory and Ryan failed miserably, although it’s safe to say he’s a completely different player nowadays and he showed once again last week in New Orleans that he can make every throw in the NFL. Will the Bucs get back on track this week or will the legend of Matt Ryan continue to grow?

Other Notable Games:

Steelers (10-3) at Ravens (9-4), 4:15 PM ET CBS
Call this game “Sunday’s Best III” or “Sunday’s Best 1A.” Whatever you call it, it’s going to be one of the best games of week. Pittsburgh remains one game ahead of Baltimore in the AFC North and currently has the head to head advantage after beating the Ravens earlier in the year. No team is playing better defensively right now than Pittsburgh, but the Ravens have suddenly hit their offensive stride in recent weeks and still boasts one of the best defenses in the league. This game might wind up being a 6-3 final.

Vikings (8-5) at Cardinals (8-5), 4:05 PM ET FOX
The Cardinals may have locked up the NFC West crown last week, but they still have plenty to play for as they try to improve their playoff seeding. And with the Bears’ victory over the Saints on Thursday night, the Vikings must win to stay one game ahead of Chicago in the NFC North. Can backup Tarvaris Jackson lead Minnesota to victory?

Broncos (8-5) at Panthers (10-3), 4:15 PM ET, CBS
With their win over Tampa on Monday night, many purists are talking about Carolina possibly being the No. 1 seed in the NFC come playoff time. But they’ll get a challenge this Sunday from a Denver team trying to clinch the AFC West crown.

Bills (6-7) at Jets (8-5), 1:00 PM ET, CBS
After losing two straight, the Jets now find themselves in a three-way tie with the Dolphins and Patriots for first place in the AFC East. Can they get back on track or will the Bills play spoiler?