Let’s take an early look at Jeff Sagarin’s college basketball ratings. I’ve found that his Predictor is a solid way to pick winners when it’s time to fill out my March Madness bracket. Over the past four years, when a team has at least a two-point advantage in Predictor, they are 156-42 (78.8%). When the difference between two teams is less than two points, the favorite is 27-24 (52.9%) over the same span.
Here’s a look at Sagarin’s top 10 teams in terms of overall rating, which is “a synthesis of the two diametrical opposites, ELO CHESS and PURE POINTS (PREDICTOR).”

As it stands, Ohio State, Kansas and Duke are favorites to make the Final Four because they are at least two-point Predictor favorites over everyone else in the field. This assumes that these three teams are in different regions, of course. The next highest team, Texas, would be a virtual toss-up with four teams: Pitt, Purdue, BYU and Washington.
You can see Sagarin’s full ratings here.
Currently, Joe Lunardi of ESPN has Duke, Ohio State, Texas and Pitt as the four #1 seeds, with Kansas as a #2 seed in Duke’s region. As it stands, Duke and Kansas would be a toss-up in the Southwest Regional Final.