Odds makers have released the point spreads for Week 4 in college football. Below are a list of odds for the top 25 teams and a quick-hit look at some of the marquee matchups.

No. 9 Miami at No. 11 Virginia Tech, Saturday 3:30PM ET
Quarterback Jacory Harris and head coach Randy Shannon have made the Canes relevant again in college football. Following wins over two ranked opponents (Florida State and Georgia Tech, respectively), Miami gets another challenge this week in Blacksburg. In their meeting last year, the Canes edged the Hokies 16-14 at Dolphin Stadium, but the last time these two programs squared off in Blacksburg, VA Tech rolled to a 44-14 victory.
Opening Odds: Miami –2.5.

Illinois at No. 13 Ohio State, Saturday, 3:30PM ET
The Buckeyes open their Big Ten schedule on Saturday when they host the Illini in Columbus. OSU rebounded from their loss to USC two weeks ago by dropping Toledo 38-0 last weekend. Illinois earned its first win of the year by trouncing Illinois State 45-17, although Missouri handed the Illini a 37-9 beating the week prior. The last time these two teams met in Columbus, Illinois shocked Ohio State 28-21 thanks to quarterback Juice Williams’ four touchdown passes.
Opening Odds: Ohio State –14.5.

No. 1 Florida at Kentucky, Saturday, 6:00PM ET
Is this a letdown week for the Gators? The No. 1 team in the nation will make its first road trip of the season after starting the year 3-0 at home. Florida will take on a 2-0 Kentucky team that has a lot of confidence after beating Louisville in a thrilling 31-27 contest in Lexington last Saturday. The Gators hammered Rich Brooks’ Wildcats 63-5 in Gainesville last season, although Kentucky made things respectable with Florida two years ago in Lexington before falling 45-37.
Opening Odds: Florida –22.

Top 25 Odds:

Thursday, September 24
No. 4 Ole Miss -3
South Carolina +3

Saturday, September 26
No. 1 Florida –22
Kentucky +22

UTEP +34
No. 2 Texas -34

Arkansas +15.5
No. 3 Alabama –15.5

Iowa +10
No. 5 Penn State -10

No. 6 California -7
Oregon +7

No. 7 LSU -14
Mississippi State +14

No. 8 Boise State -17
Bowling Green +17

No. 9 Miami –2.5
No. 11 Virginia Tech +2.5

Washington State +44.5
No. 12 USC –44.5

Illinois +14.5
No. 13 Ohio State –14.5

Fresno State +15.5
No. 14 Cincinnati –15.5

No. 15 TCU +3
Clemson -3

Texas Tech +1
No. 17 Houston -1

South Florida +14.5
No. 18 Florida State –14.5

Colorado State +14.5
No. 19 BYU –14.5

Southern Miss +13.5
No. 20 Kansas –13.5

Arizona State +12.5
No. 21 Georgia –12.5

No. 22 North Carolina +2.5
Georgia Tech –2.5

Indiana +2.5
No. 23 Michigan –2.5

No. 24 Washington +7
Stanford -7

LA-Lafayette +26.5
No. 25 Nebraska –26.5

Check out a complete list of odds at Bullz-Eye.com.