Considering No. 1 Florida opened as a 24-point favorite, one would assume that they won’t face much of a challenge this Saturday night. Mississippi State is just 3-4 on the year and has lost three of their last four games. Their most significant win came on the road against a Vanderbilt team that is just 2-5 on the year.

But there are several factors that should concern the Gators as they get ready to do battle with the Bulldogs on Saturday night:

- The Gators haven’t won in Starkville since 1985. They were defeated on Mississippi State’s home turf in 1992, 2000 and most recently in 2004.

- Florida could be down three defensive starters, including linebacker Brandon Spikes, and defensive tackles Jaye Howard and Lawrence Marsh. Spikes re-injured his left groin last week and missed most of Florida’s win over Arkansas. With him on the sidelines, the Razorbacks rushed for 133 yards and finished with 357 yards of total offense.

- Mississippi State head coach Dan Mullen severed as Florida’s quarterback coach and offensive coordinator from 2005 to 2008. If anyone knows how to exploit Tim Tebow and the rest of the Gators’ offense, it would be Mullen.

- Despite their losing record, the Bulldogs have the 13th best rushing offense in the nation and are averaging 219 yards per game on the ground this season. Senior Anthony Dixon has rushed for over 100 yards in each of his last five games, including a 138 and a 139-yard effort in his last two outings.

At the end of the day, Florida will have the better team on Saturday night. Even without Spikes, Howard and Marsh, they have enough depth defensively to limit how effective Mississippi State’s offense can be. But there are more than enough factors that should have Urban Meyer concerned about a potential upset, none bigger than the Gators’ poor showings in previous trips to Starkville.

Will Mississippi State shock the college football word this weekend and knock off the No. 1 team in the nation?