The 49ers’ loss in Minnesota on Sunday is the kind of defeat that can deflate a team. But with Mike Singletary in charge, I don’t foresee that happening.

San Francisco flat out blew a win yesterday. Had the Niners not been in a base defense when Greg Lewis got past coverage and Brett Favre found him in the back of the end zone with only seconds remaining, the 49ers would still be undefeated. (And with another win against the Rams coming in Week 4.)

While addressing the media following the loss, Singletary said: “There’s nothing to look at the floor for. We’re gonna get better. We will see them again in the playoffs.”

Singletary isn’t going to allow a good Niners team to dwell on this loss, especially when San Fran clearly has enough talent on its roster to make the playoffs. While losing running back Frank Gore to an injured ankle will hurt, the Niners did a nice job building depth this offseason when they drafted Glen Coffee.

The Niners had several positives come out of their game yesterday, including quarterback Shaun Hill proving that he can make plays in the passing game. The defense is already good enough to hang with most opponents on Sundays and in Singletary, San Fran has a head coach that has instilled hard work and focus into his team.

Ironically, the Niners are probably the class of a weak NFC West considering the Seahawks and Cardinals look vulnerable and the Rams are, well, the Rams. The division is there for the taking and something tells me that San Fran’s loss in Minnesota will only motivate them.

It’s amazing how unsung heroes emerge every week in the NFL.

For the Vikings, the unsung hero in their 27-24 win over the 49ers was receiver Greg Lewis (yes, the same Greg Lewis that never developed in Philadelphia), who made an unbelievable catch on a 32-yard pass from Brett Favre with two seconds remaining to propel Minnesota to victory.

Things looked bleak for the Vikes, who had relinquished several leads throughout the game and who appeared destined for a loss trailing 24-20 with only 1:29 left in the fourth. But Favre led Minnesota to the 49ers’ 32-yard line and with only 12 seconds remaining, zipped a pass to Lewis to earn an improbable win.

For the Niners, things went from bad to worse when it was discovered that running back Frank Gore would probably miss at least the next two weeks with a high ankle sprain. He rushed just one time for four yards against Minnesota before leaving the game.

The good news for San Fran is that although the Vikings took away the Niners’ running game, Shaun Hill was able to make plays threw the air. Vernon Davis had a big day, hauling in seven passes for 96 yards and two touchdowns as San Fran beat Minnesota’s Cover 2 defense by attacking the middle of the field.

The bad news for San Fran is that it blew the final play. Why were they in a normal defense when the game was on the line and Minnesota had to go 40 yards to score a touchdown to win? The 49ers should have had more defenders back to protect the only play that could hurt them and shouldn’t have allowed Lewis to sneak behind their coverage.

But Mike Singletary and the Niners will learn from the loss and move on. This is still a solid team and should be competitive all season.

Along with the odds and over/under totals, here’s a look at some of the marquee matchups for Week 3 in the NFL.

Falcons (2-0) at Patriots (1-1), Sunday, 1:00PM ET
This will be a great test to see where both of these teams currently lie. The Falcons are 2-0 with wins over two struggling 2008 playoff teams, while the Patriots could very easily be 0-2 right now. Behind quarterback Matt Ryan’s (108.5 QB Rating) great start, Atlanta’s offense is gearing up for big things this season, but the defense is giving up 5.1 YPC and just lost starting DT Peria Jerry for the year. New England has its own defensive problems without middle linebacker Jerod Mayo and Tom Brady still hasn’t looked comfortable on his surgically repaired knee. It would be unwise to doubt Bill Belichick and the Patriots, but the Falcons would go a long way in proving that they’re a legitimate Super Bowl contender with a win at Foxboro.
Odds: Patriots –4.

49ers (2-0) at Vikings (2-0), Sunday, 1:00PMET
Who would have thought that the only matchup this week featuring two 2-0 teams would be the 49ers at Vikings? San Francisco’s defense has been solid in the first two games, yielding less than 300 total yards per game and limiting opponents to only 13 PPG. But neither Arizona nor Seattle posed the rushing threat that Adrian Peterson and Minnesota will provide this Sunday. This will be a great test to see where Mike Singletary’s team is and whether or not the Niners are legitimate playoff contenders. Can Shaun Hill beat the Vikings through the air if/when the Williams Wall takes away Frank Gore?
Odds: Vikings –7.

Titans (0-2) at Jets (2-0), Sunday, 1:00PM ET
Panic hasn’t set in yet for Jeff Fisher and the Titans, although a loss this week in East Rutherford would make things unsettling in Tennessee. Jets’ rookie Mark Sanchez has looked more like a five-year pro than a quarterback with only two career starts under his belt, but will this be the week that he finally suffers some growing pains? Tennessee’s defense has a way of making opposing quarterbacks look bad, although that certainly wasn’t the case last week when Houston’s Matt Schaub threw a career high four touchdown passes against the Titans. If Fisher’s squad falls to 0-3, the Titans may never recover. On the flip side, if the Jets start 3-0 they’ll set themselves up for making a run at the AFC East crown.
Odds: Jets –2.5.

(2-0) Colts at Cardinals (1-1), Sunday, 8:20PM ET
If you like watching quick-tempo offenses, then the Sunday night game will be right up your alley. The Colts defeated the Dolphins on Monday might despite only running 35 plays, which means Peyton Manning and the rest of Indy’s offense is already in midseason form. The Cards bounced back from their opening week loss to the 49ers by pounding the Jaguars last Sunday thanks to Kurt Warner’s amazing 24-for-26 passing day. Watching Manning and Warner dissect the opposing defense is going to be one of the more intriguing things to watch in Week 3.
Odds: Cardinals -2.5.

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